DsbA-L Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | DsbA-L |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | serum |
| Size | 100 µL |
| Concentration | Titrated value sufficient to run approximately 10 mini blots. |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-DsbA-L antibody is directed against DsbA-L. Anti-DsbA-L antibody is neat antiserum prepared from monospecific antiserum by delipidation and defibrination. Reactivity against DsbA-L occurs from mouse and human sources. Reactivity against DsbA-L from other sources is unknown. DsbA-L Antibody detects Disulfide-bond-A oxidoreductase-like protein (DsbA-L, previously named as GST Kappa) which is an adiponectin-interacting protein. DsbA-L is highly expressed in adipose tissue, and its expression level is negatively correlated with obesity in mice and humans. DsbA-L expression in 3T3-L1 adipocytes is stimulated by the insulin sensitizer rosiglitazone and inhibited by the inflammatory cytokine TNFalpha. Polymorphism of DsbA-L gene has recently been implicated in insulin secretion and body fat distribution. Overexpression of DsbA-L promotes adiponectin multimerization while suppressing DsbA-L expression by RNAi markedly and selectively reduces adiponectin levels and secretion in 3T3-L1 adipocytes. Recent studies identify DsbA-L as a key regulator for adiponectin biosynthesis. Anti-DsbA-L Antibody is ideal for investigators involved in Cell Signaling and Cell Metabolism. |
| Immunogen | Anti-DsbA-L Antibody was produced in rabbit by repeated immunizations with full length recombinant mouse DsbA-L protein |
| Other Names | Glutathione S-transferase kappa 1, GST 13-13, GST class-kappa, GSTK1-1, Glutathione S-transferase subunit 13, Disulfide-bond-A oxidoreductase-like protein, DsbA-L |
| Gene, Accession # | Gstk1, Gene ID: 76263, NCBI: NP_083831.1, UniProt: Q9DCM2 |
| Catalog # | 100-401-D29 |
| Price | $475 |
| Order / More Info | DsbA-L Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | PubMed: 31130066 |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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