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Antigenic Specificity | IL-17RA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-IL-17RA Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. IL-17RA antibody is human, mouse and rat reactive. Multiple isoforms of IL-17RA are known to exist. This antibody is predicted to not cross-react with other IL-17 receptor subunits. Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes (1). It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F (1,2). IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis (3,4). Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections (5). |
Immunogen | Anti-IL-17RA antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the N-terminus of human IL-17RA. |
Other Names | IL-17RA Antibody, CD217, IL17R, CANDF5, CDw217, IL-17RA, hIL-17R, Interleukin-17 receptor A, IL-17 receptor A |
Gene, Accession # | IL17RA, Gene ID: 23765, NCBI: NP_055154, UniProt: Q96F46 |
Catalog # | 600-401-BU9 |
Price | $475 |
Order / More Info | IL-17RA Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |