Lgi1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Lgi1 |
| Clone | S283-7 |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2a |
| Format | PerCP conjugate |
| Size | 100 µg |
| Concentration | 1mg/mL |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-LGI1 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests that it is 100% identical to rat, 98% identical to human and ~50% identical to LGI2, LGI3, and LGI4. The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist; this LGI1 antibody will recognize only the longer form. Anti-LGI1 is ideal for research in Neuroscience and Cancer. |
| Immunogen | Anti-LGI1 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 37-113 (LRRNT domain and first LRR repeat) of mouse LGI1. |
| Other Names | ADLTE, ADPAEF, ADPEAF, Epitempin 1, EPT, ETL1, IB1099, leucine rich glioma inactivated 1, OTTHUMP00000020121, OTTHUMP00000020137 |
| Gene, Accession # | Lgi1, Gene ID: 56839, NCBI: NP_064674.1, UniProt: Q9JIA1 |
| Catalog # | 200-365-W73 |
| Price | $495 |
| Order / More Info | Lgi1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.