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Antigenic Specificity | Caspase-13 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | ion exchange purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Caspase-13 Antibody is purified by ion exchange chromatography. Cross reactivity with Caspase-13 from other sources has not been determined. Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 beta Converting Enzyme) and caspase-13. Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines. |
Immunogen | Anti-Caspase-13 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid peptide near the N-terminus of human Caspase-13. |
Other Names | Caspase-13 Antibody, CASP13, Caspase-13, Evolutionary related interleukin-1-beta-converting enzyme, CASP-13 |
Gene, Accession # | CASP13, Gene ID: 338039, NCBI: NP_788811.1, UniProt: O75601 |
Catalog # | 600-401-AD0 |
Price | $475 |
Order / More Info | Caspase-13 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |