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Antigenic Specificity | Caspase-6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Caspase-6 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Depending on cell lines or tissues used, either full-length or other cleavage products may be observed. Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-6 is an executioner caspase that was identified based on its homology with human caspases 2 and 3 as well as the C. elegans cell death protein CED-3. It possesses two isoforms, of which only the longer form possesses protease activity. Caspase-6 is highly expressed in adult brain and may play a role in several neuronal pathologies. |
Immunogen | Anti-Caspase-6 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide from near the amino-terminus of human Caspase-6. |
Other Names | Caspase-6 Antibody, MCH2, MCH2, Caspase-6, Apoptotic protease Mch-2, CASP-6 |
Gene, Accession # | CASP6, Gene ID: 839, NCBI: NP_001217, UniProt: P55212 |
Catalog # | 600-401-AD8 |
Price | $475 |
Order / More Info | Caspase-6 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |