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Antigenic Specificity | NOD5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-NOD5 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with NOD5 from other sources has not been determined. NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-kB and JNK pathways by inducing reactive oxygen species production. |
Immunogen | Anti-NOD5 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the N-terminus of human NOD5. |
Other Names | NOD5 Antibody, NOD5, NOD9, NOD26, DLNB26, CLR11.3, NOD5, NLR family member X1, Nucleotide-binding oligomerization domain protein 26 |
Gene, Accession # | NLRX1, Gene ID: 79671, NCBI: NP_078894, UniProt: Q86UT6 |
Catalog # | 600-401-DD1 |
Price | $475 |
Order / More Info | NOD5 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |