Edit |   |
---|---|
Antigenic Specificity | LNPEP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-LNPEP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least three isoforms are known to exist; this antibody will detect all three isoforms. Despite its predicted molecular weight, LNPEP often migrates at 165kD in SDS-PAGE. LNPEP, also known as insulin-responsive aminopeptidase (IRAP), was initially identified as an abundant protein that is associated with specialized endosomes termed GLUT4 storage vesicles (GSVs) in adipocytes. The luminal domain of LNPEP contains an aminopeptidase activity that is involved in peptide hormone processing and antigenic peptide processing. LNPEP is also a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to the GSVs. |
Immunogen | Anti-LNPEP antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the C-terminus of human LNPEP. |
Other Names | LNPEP Antibody, CAP, IRAP, PLAP, P-LAP, OTASE, Leucyl-cystinyl aminopeptidase, Insulin-regulated membrane aminopeptidase, Cystinyl aminopeptidase |
Gene, Accession # | LNPEP, Gene ID: 4012, NCBI: NP_005566, UniProt: Q9UIQ6 |
Catalog # | 600-401-CL8 |
Price | $475 |
Order / More Info | LNPEP Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |