TBC1D1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | TBC1D1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-TBC1D1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TBC1D1 from other sources has not been determined. TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain and presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2/USP6, yeast Bub2, and CDC16. TBC1D1 and TBC1D4 (AS160) have been demonstrated to be Rab GAPs (GTPase-activating proteins) that link upstream to Akt and phosphoinositide 3-kinase and downstream to Rabs involved in trafficking of GLUT4 vesicles. TBC1D1 regulates insulin-mediated GLUT4 translocation through its GAP activity, and is a likely Akt substrate. Mutations in the Tbc1d1 gene lead to some cases of severe human obesity. |
| Immunogen | Anti-TBC1D1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 22 amino acid synthetic peptide from near the C-terminus of human TBC1D1. |
| Other Names | TBC1D1 Antibody, TBC, TBC1, KIAA1108, TBC1 domain family member 1 |
| Gene, Accession # | TBC1D1, Gene ID: 23216, NCBI: NP_001240841.1, UniProt: Q86TI0 |
| Catalog # | 600-401-EZ8 |
| Price | $475 |
| Order / More Info | TBC1D1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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