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Antigenic Specificity | Collagen Type III |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, bovine |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 50 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This product has been prepared by immunoaffinity chromatography using immobilized antigens. Some class-specific anti-collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues. This antibody reacts with most mammalian Type III collagens and has expected cross-reactivity with Type I and negligible cross reactivity with Type II, IV, V or VI collagens. Non-specific cross-reaction of anti-collagen antibodies with other human serum proteins or non-collagen extracellular matrix proteins has not been tested. In muscle tissue, collagen serves as a major component of the endomysium. Collagen constitutes one to two percent of muscle tissue, and accounts for 6% of the weight of strong, tendinous muscles. A collagen may be defined as a protein containing sizable domain(s) of triple-helical conformation. Type IV collagen is a major macromolecular constituent of basement membranes and can be readily isolated from basement-membrane-rich tissues or highly vascularized tissues such as the placental villi. This collagen appears to be largely restricted to structures identifiable as basement membranes. In contrast, type VI collagen appears to be prevalent in several tissues even though it has been isolated largely from placental villi preparations. The extent to which type VII and VIII collagens are distributed is not known. |
Immunogen | Collagen Type III from human and bovine placenta |
Other Names | rabbit anti-Collagen Type III antibody fluorescein conjugation, FITC conjugated rabbit anti-Collagen Type III antibody, Collagen type III alpha 1 antibody, Collagen type III alpha antibody, EDS4A antibody, Ehlers Danlos syndrome type IV, autosomal dominant antibody, Fetal collagen antibody, COL3A1, Collagen alpha-1 (III) chain |
Gene, Accession # | COL3A1, Gene ID: 1281, NCBI: NP_000081.1, UniProt: P02461 |
Catalog # | 600-402-105 |
Price | $495 |
Order / More Info | Collagen Type III Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |