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Antigenic Specificity | XKR8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-XKR8 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. XKR8 antibody is human reactive. At least two isoforms are known to exist; this antibody will detect both isoforms. The XK Kell blood group complex subunit-related family member 8 (XKR8) is a member of a family of proteins that promote the phagocytosis of dying cells by altering the phospholipid distribution of the plasma membrane (1). XKR8 is thought to be a ``scramblase'', an enzyme that eliminates the asymmetry of phospholipid distribution in the plasma membrane. In apoptotic cells, XKR8 promotes the cell-surface exposure of phosphatidylserine (PtdSer) which serves as a signal for phagocytosis (1,2). |
Immunogen | Anti-XKR8 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid peptide near the C-terminus of human XKR8. |
Other Names | XKR8 Antibody, XRG8, hXkr8, XRG8, XK-related protein 8 |
Gene, Accession # | XKR8, Gene ID: 55113, NCBI: NP_060523.2, UniProt: Q9H6D3 |
Catalog # | 600-401-GA1 |
Price | $475 |
Order / More Info | XKR8 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |