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Antigenic Specificity | RAIDD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-RAIDD Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with RAIDD from other sources has not been determined. Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD-containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP-associated ICH-1/CED-3-homologous protein with DD) and CRADD (caspase and RIP adapter with DD)1, RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals1, 3. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR-1. |
Immunogen | Anti-RAIDD antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the internal region of human RAIDD. |
Other Names | RAIDD Antibody, MRT34, RAIDD, Death domain-containing protein CRADD, Caspase and RIP adapter with death domain |
Gene, Accession # | CRADD, Gene ID: 8738, NCBI: AAB42217, UniProt: P78560 |
Catalog # | 600-401-DV9 |
Price | $475 |
Order / More Info | RAIDD Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |