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Antigenic Specificity | ILPIP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ILPIP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ILPIP from other sources has not been determined. ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family. Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1b converting enzyme of Fas-induced apoptosis. This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival, suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed. |
Immunogen | Anti-ILPIP antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the internal region of human ILPIP. |
Other Names | ILPIP Antibody, PAPK, ILPIP, ILPIPA, ALS2CR2, CALS-21, PRO1038, STE20-related kinase adapter protein beta, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein, STRAD beta |
Gene, Accession # | STRADB, Gene ID: 55437, NCBI: NP_061041, UniProt: Q9C0K7 |
Catalog # | 600-401-BY0 |
Price | $475 |
Order / More Info | ILPIP Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |