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Antigenic Specificity | TSHZ3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TSHZ3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TSHZ3 from other sources has not been determined. The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. In mice, the known three TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting that they play a role in the establishment of regional identity and specification of cell types within the brain. Both TSHZ3 and TSHZ1 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4. Recent experiments have also suggested this family of proteins may be involved in carcinogenesis. |
Immunogen | Anti-TSHZ3 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide near the N-terminus of human TSHZ3. |
Other Names | TSHZ3 Antibody, TSH3, ZNF537, KIAA1474, TSH3, Teashirt homolog 3, Zinc finger protein 537 |
Gene, Accession # | TSHZ3, Gene ID: 57616, NCBI: NP_065907.2, UniProt: Q63HK5 |
Catalog # | 600-401-FR5 |
Price | $475 |
Order / More Info | TSHZ3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |