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Antigenic Specificity | MALT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-MALT1 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. MALT1 antibody is human, mouse and rat reactive. At least two isoforms of MALT1 are known to exist; this antibody will detect both isoforms. MALT1 was initially identified as a novel gene that was recurrently rearranged in t(11;18)(q21;q21) mucosa-associated lymphoid tissue lymphomas along with the apoptosis inhibitor protein c-IAP2 (1). MALT1, along with the proteins CARMA1 and Bcl10 form an NF-kappaB-activating complex, termed the CBM signalsome, that acts downstream of lymphocyte antigen receptors as well as many other non-lymphoid cell-surface receptors that play a role in multiple cellular functions (2,3). MALT1 has proteolytic activity, and this activity is critical for full NF-kappaB response in T cell activation (4). |
Immunogen | Anti-MALT1 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the C-terminus of human MALT1. |
Other Names | Mucosa associated lymphoid tissue lymphoma translocation 1, IMD12, MLT, MLT1 |
Gene, Accession # | MALT1, Gene ID: 10892, NCBI: NP_006776, UniProt: Q9UDY8 |
Catalog # | 600-401-CQ0 |
Price | $475 |
Order / More Info | MALT1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |