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Antigenic Specificity | MATN2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-MATN2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with MATN2 from other sources has not been determined. Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks. The matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled coil alpha-helical module. MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices. The matrilin genes are strictly and differently regulated and their expression may serve as markers for cellular differentiation and diseases such as astrocytoma and liver carcinoma. Recent studies show that MATN2 is a permissive substrate for axonal growth and cell migration, and it is required for successful nerve regeneration. |
Immunogen | Anti-MATN2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide from near the C-terminus of human MATN2. |
Other Names | MATN2 Antibody, Matrilin-2 |
Gene, Accession # | MATN2, Gene ID: 4147, NCBI: NP_085072, UniProt: O00339 |
Catalog # | 600-401-CR3 |
Price | $475 |
Order / More Info | MATN2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |