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Antigenic Specificity | Avian Influenza Neuraminidase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Avian Influenza Neuraminidase Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with Avian Influenza Neuraminidase with Virus based on 100% homology with the immunizing sequence. Cross-reactivity with Avian Influenza Neuraminidase from other sources has not been determined. Avian Influenza Neuraminidase Antibody detects internal portion of the protein. Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. Although it has been known that cleavage site and glycosylation patterns of the HA protein play important roles in determining the pathogenicity of H5 avian influenza viruses, it has only recently been shown that an additional glycosylation site within the globular head of the NA protein also contributes to the high virulence of the H5N1 virus. Anti-Avian Influenza Neuraminidase antibodies are ideal for investigators involved in infectious disease research. |
Immunogen | Avian Influenza Neuraminidase Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to an internal region of the avian influenza neuraminidase protein. Efforts were made to use relatively conserved regions as the antigen. |
Other Names | Neuraminidase |
Gene, Accession # | NCBI: AAT76166, UniProt: Q692M2 |
Catalog # | 600-401-G80 |
Price | $475 |
Order / More Info | Avian Influenza Neuraminidase Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |