Amyloid Fibrils (OC) Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Amyloid Fibrils (OC) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 100 µL |
| Concentration | n/a |
| Applications | ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Amyloid Fibrils (OC) Antibody was purified by Protein A chromatography. A BLAST analysis was used to suggest cross-reactivity with Amyloid Fibrils (OC) from Human based on 100% homology with the immunizing sequence. Expected to detect in mouse and rat based on species homology. Recognizes generic epitopes common to many amyloid fibrils and fibrillar oligomers, but not prefibrilllar oligomers or natively folded proteins. Cross-reactivity with Amyloid Fibrils (OC) from other sources has not been determined. Neuroscience research. Amyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibers. These include the amyloid-β peptide plaques and tau neurofibrillary tangles in senile plaques of Alzheimer's symptomology, the deposition of α-synuclein in the Lewy bodies of Parkinson's disease, and accumulation of polyglutamine-containing aggregates in Huntington's disease. |
| Immunogen | Amyloid Fibrils (OC) Antibody was produced from whole rabbit serum prepared by repeated immunizations with fibrils prepared from human Aβ42 synthetic peptide. |
| Other Names | Amyloid OC, Fibrils, Amyloid Oligomer αβ, A11, Amyloid beta A4 protein, ABPP, APPI, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, PreA4, Protease nexin-II, APP, A4, AD1 |
| Gene, Accession # | APP UniProt: P05067 |
| Catalog # | 200-401-E87 |
| Price | $455 |
| Order / More Info | Amyloid Fibrils (OC) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | PubMed: 29843431 // 31693761 // 33504788 |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.