Histone H3 K36ac Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Histone H3 K36ac |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, C. elegans |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 50 µg |
| Concentration | 1.0 mg/mL |
| Applications | Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Histone H3 [ac Lys36] was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with human Histone H3.2. A BLAST analysis was used to suggest cross-reactivity with Human, mouse, and C. elegans. Predicted to react with many species including rat, chicken, Xenopus, Drosophila, and plant based on 100% sequence homology. Cross-reactivity with Histone H3 from other sources has not been determined. Histone H3 acetylation at lysine 36 results from the activity of GCN5, which regulates transcription. H3K36ac is usually found in the promoters of RNA polymerase II-transcribed genes. When acetylation of this lysine is replaced by methylation, the activation of transcription is eliminated. This switch-like activity seems to determine the chromatin function found in transcription units. Set2 associates with RNA polymerase II and histone H3 at lysine 36, and seems to be responsible for proper acetylation of coding regions. The co-activity of Set2 and Rpd3S is important for ensuring that transcription of intragenic sequences does not occur, and is related to the acetylation and methylation of histone H3 at lysine 36. Anti-Histone H3 are ideal for researchers interested in Chromatin Modifiers, Chromatin Research, Histones and Modified Histones, and Epigenetics research. |
| Immunogen | Histone H3 [ac Lys36] affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic acetylated peptide surrounding Lysine 36 of human Histone H3.2. |
| Other Names | rabbit anti-Histone H3 Ac Lys36 antibody, H3.3B, H3 histone, family 3A, H3.3AH3F3H3F3B, histone H3.3, MGC87783, MGC87782, H3K36ac |
| Gene, Accession # | HIST2H3C, Gene ID: 126961, NCBI: NP_001005464, UniProt: Q71DI3 |
| Catalog # | 600-401-I89 |
| Price | $495 |
| Order / More Info | Histone H3 K36ac Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | PubMed: 33522486 |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
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https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.