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Antigenic Specificity | ZBTB7A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ZBTB7A Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of ZBTB7A are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members. The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB7A, also known as LRF, was initially identified as a potential target of the LAZ-3/BCL-6 oncogene. Later reports demonstrated that it could bind to the wild-type IST (inducer of short transcripts) elements of HIV-1 long terminal repeats (LTRs) and stimulate Tat activity on the HIV-1 LTR. More recently it ZBTB7A has been recognized as a proto-oncogene whose overexpression contributes to malignancy in breast cancer and functions as a co-repressor of the androgen receptor in prostate cancer cells. |
Immunogen | Anti-ZBTB7A antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the N-terminus of human ZBTB7A. |
Other Names | ZBTB7A Antibody, LRF, FBI1, FBI-1, ZBTB7, ZNF857A, pokemon, LRF, Zinc finger and BTB domain-containing protein 7A, Factor binding IST protein 1 |
Gene, Accession # | ZBTB7A, Gene ID: 51341, NCBI: NP_001304919.1, UniProt: O95365 |
Catalog # | 600-401-GC1 |
Price | $475 |
Order / More Info | ZBTB7A Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |