VTCN1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | VTCN1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1.0 mg/ml |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-VTCN1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with VTCN1 from other sources has not been determined. T cell immunity plays a critical role in host immune surveillance of tumour cell growth and metastatic spread. VTCN1, also known as B7-H4, is a member of the B7 family of immune regulatory molecules. Expressed primarily on the membrane of lymphoid cells, VTCN1 is an immunoinhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of VTCN1 is associated with certain malignancies, including ovarian and breast cancer, which may be a mechanism by which tumour cells suppress T cell immunity and facilitate tumour progression. VTCN1 may thus be a useful biomarker for the early detection of ovarian cancer. |
| Immunogen | Anti- VTCN1 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the internal region of human VTCN1. |
| Other Names | VTCN1 Antibody, B7X, B7H4, B7S1, B7-H4, B7h.5, VCTN1, PRO1291, UNQ659/PRO1291, V-set domain-containing T-cell activation inhibitor 1, Immune costimulatory protein B7-H4 |
| Gene, Accession # | VTCN1, Gene ID: 79679, NCBI: NP_001240778.1, UniProt: Q7Z7D3 |
| Catalog # | 600-401-FX5 |
| Price | $475 |
| Order / More Info | VTCN1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.