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Antigenic Specificity | STAT1 R31-Me2a |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 25 µL |
Concentration | 0.84 mg/ml |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-STAT1 R31-Me2a was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with human STAT1 surrounding aa31 and is specific for Me2a. A BLAST analysis was used to suggest cross-reactivity with Human, mouse, and rat. Cross-reactivity with STAT1 from other sources has not been determined. Minimal cross reactivity shown with STAT4 and STAT5 surrounding aa31. Signal transducer and activator of transcription 1 (Stat1) belongs to a family of cytoplasmic transcription factors that can be activated by a cell surface receptor. Stat1 has two isoforms. Stat1 has been found to be inappropriately activated in many tumors. In addition to tyrosine phosphorylation, Stat1 is phosphorylated through a p38 mitogen-activated protein kinase (MAPK)-dependent pathway at Ser727 in response to IFN-g and other cellular stresses. Stat1 is localized in the cytoplasm and upon phosphorylation at Y701 is translocated to the nucleus. |
Immunogen | STAT1 [Asym-dimethyl Arg] affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic monomethylated peptide surrounding Arginine 31 of human STAT. |
Other Names | rabbit anti-STAT1 Asym-dimethyl Arg31 antibody, rabbit anti-STAT1 R31me2a antibody, STAT-1, STAT 1, Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84 |
Gene, Accession # | STAT1 UniProt: P42224 |
Catalog # | 600-401-GH1S |
Price | $125 |
Order / More Info | STAT1 R31-Me2a Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |