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Product Name | Recombinant Mouse CD117 (c-Kit)-Fc Chimera (carrier-free) |
Description | CD117 is a 145 kD protein tyrosine kinase also known as c-Kit and stem cell factor receptor (SCFR). It belongs to CSF-1/PDGF receptor subfamily. CD117 is a receptor for stem cell factor (SCF) or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells, and acute myeloid leukemia cells (AML). c-Kit ligand binding of CD117 induces dimerization and phosphorylation of CD117, and activates the downstream signaling, including PI3K, JAK/STAT, PLC-γ and MAPK pathways. C |
Size | 500 µg |
Concentration | n/a |
Applications | BA |
Other Names | Stem cell factor receptor, SCFR, c-kit, mast/ stem cell growth factor receptor, steel factor receptor |
Gene, Accession, CAS # | Gene ID: 16590 |
Catalog # | 790808 |
Price | $1969 |
Order / More Info | Recombinant Mouse CD117 (c-Kit)-Fc Chimera (carrier-free) from BIOLEGEND |
Product Specific References | n/a |