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Product Name | Recombinant MU B7-H1 (PD-L1, CD274)-Fc Chimera (CF) |
Description | PD-L1 is a type I transmembrane protein of 290 amino acids, and it is a member of the B7 family. Mouse PD-L1 has 70% amino acid identity to its human orthologue. Binding of PD-L1 to its receptor PD-1 leads to the inhibition of T cell receptor-mediated lymphocyte proliferation and cytokine secretion. PD-L1 induces IL-10 production in T cells stimulated with low levels of anti-CD3. PD-L1/PD-1 interaction suppresses immune responses against autoantigens and tumors and plays an important role in the |
Size | 10 µg |
Concentration | n/a |
Applications | BA |
Other Names | CD274, Programmed cell death 1 ligand 1 (PD-L1), B7 homolog 1 (B7h1) |
Gene, Accession, CAS # | Gene ID: 60533 |
Catalog # | 758202 |
Price | $54 |
Order / More Info | Recombinant MU B7-H1 (PD-L1, CD274)-Fc Chimera (CF) from BIOLEGEND |
Product Specific References | PubMed: 31040917 |