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Product Name | CCR5 |
Description | Magic™ Membrane Protein Human CCR5 (C-C motif chemokine receptor 5). CCR5 is a receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates. CCR5 is G protein-coupled receptor (GPCR) which regulates trafficking and effector functions of memory/effector T-lymphocytes, macrophages, and immature dendritic cells. It also serves as the main coreceptor for the entry of R5 strains of human immunodeficiency virus (HIV-1, HIV-2). Histidine tag fused to the N-terminal end of the protein. Purity >50% by SDS-Page and Coomassie Blue staining |
Size | n/a |
Concentration | n/a |
Applications | Screening & display technologies. The protein is for research use only and is not approved for use in humans or in clinical diagnosis. |
Other Names | CKR5, CCR-5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5 |
Gene, Accession, CAS # | Gene ID: 1234, UniProt: P51681 |
Catalog # | MP0009F |
Price | please inquire |
Order / More Info | CCR5 from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |