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Product Name | Recombinant Human Mannan-binding lectin serine protease 1 (MASP1) |
Description | Sequence: 20-699. Full Length of Mature Protein. Purity >90% as determined by SDS-PAGE. Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5. MW: 93.03kD |
Size | 0.01 mg (E. coli), 0.01 mg (Yeast), 0.05 mg (E. coli) |
Concentration | n/a |
Applications | n/a |
Other Names | [mannan-binding lectin serine protease 1 isoform 3; Mannan-binding lectin serine protease 1; mannan-binding lectin serine protease 1; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor); Complement factor MASP-3; Complement-activating component of Ra-reactive factor; Mannose-binding lectin-associated serine protease 1; MASP-1], [MASP1; MASP1; 3MC1; MAP1; MASP; RaRF; CRARF; MASP3; MAp44; PRSS5; CRARF1; CRARF; CRARF1; PRSS5; MASP-1; RaRF] |
Gene, Accession, CAS # | [MASP1], Gene ID: 5648, NCBI: NP_001027019.1, UniProt: P48740 |
Catalog # | MBS958279 |
Price | $160, $175, $200 |
Order / More Info | Recombinant Human Mannan-binding lectin serine protease 1 (MASP1) from MYBIOSOURCE INC. |
Product Specific References | n/a |