Recombinant Human ICOS Ligand / B7-H2 / ICOSLG Protein (His tag) from MYBIOSOURCE INC.

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Product NameRecombinant Human ICOS Ligand / B7-H2 / ICOSLG Protein (His tag)
DescriptionPurity > 98 % as determined by SDS-PAGE. Background: Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmembrane glycoprotein with extracellular IgV and IgC domains, and binds to ICOS on activated T cells, thus delivers a positive costimulatory signal for optimal T cell function. The structural features of ICOSL are crucial for its costimulatory function. Present study shows that ICOSL displays a marked oligomerization potential, resembling more like B7-1 than B7-2. B7-H2-dependent signaling may play an active role in a proliferative response rather than in cytokine and chemokine production. The CD28/B7 and ICOS/B7-H2 pathways are both. MW: 20,120 Da
Size0.1 mg, 0.2 mg
Concentrationn/a
Applicationsn/a
Other Names[B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653, LICOS]
Gene, Accession, CAS #[ICOSLG], Gene ID: 23308, NCBI: NP_056074.1, UniProt: O75144
Catalog #MBS2545745
Price$435, $635
Order / More InfoRecombinant Human ICOS Ligand / B7-H2 / ICOSLG Protein (His tag) from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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