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Product Name | Recombinant human REF-1/APEX1 protein |
Description | Domain: 1-318aa. Recombinant human APEX1 protein, fused to T7-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 36.9 kDa (332aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. APEX1, also known as REF1 or APE1 (Apurinic / apyrimidinic endonuclease), is responsible for the incision of DNA basic sites during base excision repair. It has also been shown to stimulate the DNA binding activity of numerous transcription factors that are involved in cancer promotion and progression. APEX1 is part of the cellular response to oxidative stress and protects cells from the genotoxic and cytotoxic effect of oxidizing agents |
Size | 10ug, 50ug, 250ug |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Apurinic/apyrimidinic endodeoxyribonuclease 1, APEX nuclease, APEN, multifunctional DNA repair enzyme 1, DNA-(apurinic or apyrimidinic site) endonuclease, AP endonuclease 1, APE-1, Redox factor-1, APE, APE1, APEX, APX, HAP1, REF1 |
Gene, Accession, CAS # | NCBI: AAH19291.1, UniProt: P27695 |
Catalog # | ATGP0881 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human REF-1/APEX1 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |