Edit |   |
---|---|
Product Name | Recombinant human CLF-1/CLC protein |
Description | Domain: 28-225aa. CLCF1, also known as cardiotrophin-like cytokine factor 1, belongs to the interleukin 6 family of cytokines, which are involved in cell signaling through phosphorylation of gp130. CLCF1 has a sequence of 225-amino acids with a 27-aa signal peptide, a molecular mass of 22 kDa in mature form, and the highest homology to cardiotrophin-1 and ciliary neurotrophic factor. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. MW: 24.6 kDa (219aa). Purity > 90% by SDS-PAGE. |
Size | 20ug, 100ug, 500ug |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE,Denatured |
Other Names | Cardiotrophin-like cytokine factor 1, BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6 |
Gene, Accession, CAS # | NCBI: NP_037378, UniProt: Q9UBD9 |
Catalog # | ATGP1179 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human CLF-1/CLC protein from NKMAX Co. Ltd. |
Product Specific References | n/a |