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Product Name | Recombinant human LILRB1/CD85j/ILT2 protein |
Description | Domain: 24-461aa. Recombinant human LILRB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 48.5kDa (446aa). Purity > 95% by SDS-PAGE. LILRB1, also known as leukocyte immunoglobulin like receptor B1, is a member of the leukocyte immunoglobulinlike receptor (LIR) family. The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. It is also expressed on the surface of B cells and monocytes, as well as subsets of NK cells, memory/effector CD8+ T cells, gamma δ T cells, and monocyte-derived dendritic cells. It binds to MHC-I as well as non-classical MHC-I molecules and the MHC-I mimetic UL18 encoded by cytomegalovirus |
Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
Concentration | 0.25mg/ml (determined by absorbance at 280nm) |
Applications | SDS-PAGE, Bioactivity |
Other Names | Leukocyte immunoglobulin-like receptor subfamily B member 1, LIR-1, LIR1, Leukocyte immunoglobulin-like receptor 1, CD85 antigen-like family member J, Immunoglobulin-like transcript 2, ILT-2, ILT2, Ig-like transcript 2, Monocyte/macrophage immunoglobulin-like receptor 7, MIR-7, MIR7, CD_antigen, CD85j, CD85 antigen-like family member J, PIRB, PIR-B, leucocyte Ig-like receptor B1, leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1, monocyte/macrophage immunoglobulin-like receptor 7, myeloid inhibitory receptor 7 |
Gene, Accession, CAS # | NCBI: NP_006660.4, UniProt: Q8NHL6 |
Catalog # | ATGP3965 |
Price | $120, $220, $290, $480, $850, $1450, $2420 |
Order / More Info | Recombinant human LILRB1/CD85j/ILT2 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |