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Product Name | Recombinant human M-CSF protein |
Description | Domain: 33-255aa. Recombinant human CSF1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 26.1 kDa (231aa). Purity > 95% by SDS-PAGE. CSF1, also known as macrophage colony-stimulating factor 1, is a hematopoietic growth factor that is the primary regulator of the survival, proliferation, differentiation and function of mononuclear phagocytes. It is a four alpha-helical bundle cytokine and its active form is found extracellularly as a disulfide linked homodimer. This protein plays important roles in innate immunity, cancer and inflammatory diseases, including systemic lupus erythematosus, arthritis, atherosclerosis and obesity. In several conditions, activation of macrophages involves a CSF1 autocrine loop. In addition, secreted and cell-surface isoforms of CSF1 can have differential effects in inflammation and immunity |
Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
Concentration | 0.25mg/ml (determined by absorbance at 280nm) |
Applications | SDS-PAGE, Bioactivity |
Other Names | Macrophage colony-stimulating factor 1, CSF1, M-CSF, MCSF, Lanimostim, ATGP3269 |
Gene, Accession, CAS # | NCBI: NP_000748, UniProt: P09603 |
Catalog # | ATGP3565 |
Price | $105, $194, $320, $530, $750, $960, $1600 |
Order / More Info | Recombinant human M-CSF protein from NKMAX Co. Ltd. |
Product Specific References | n/a |