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Product Name | Recombinant human SLAM/CD150 protein |
Description | Domain: 21-237aa. Recombinant human SLAMF1 protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 26.7 kDa (240aa). Purity > 85% by SDS-PAGE. SLAMF1 belongs to the immunoglobulin gene superfamily and is involved in T-cell stimulation. This protein is constitutively expressed on peripheral blood memory T cells, T-cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. High-affinity for self-ligand is important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11) -dependent signal transduction operates |
Size | 4ug, 20ug, 100ug |
Concentration | 0.5mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE,Denatured |
Other Names | signaling lymphocytic activation molecule precursor, CD150, CDw150, SLAM |
Gene, Accession, CAS # | NCBI: NP_003028, UniProt: Q13291 |
Catalog # | ATGP1883 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human SLAM/CD150 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |