Description | Domain: 1-375aa. Recombinant human Serpin B5/Maspin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW: 44.2 kDa (395aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. Serpin B5/Maspin, also known as serpin family B member 5, is a tumor suppressor protein of serine proteinase inhibitor family. It plays an essential role in embryonic development through critical roles in cell adhesion. Also, it is present in normal breast and prostatic epithelial cells but down regulated in the respective carcinomas |
Other Names | Acrosomal serine protease inhibitor, IPSP, IPSP_HUMAN, PAI 3, PAI-3, PAI3, PCI, PCI-B, PLANH 3, PLANH3, Plasma serine protease inhibitor, Plasminogen activator inhibitor 3, Plasminogen activator inhibitor III, PROCI, Protein C inhibitor, Serpin A5, Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 5, Serpin peptidase inhibitor clade A member 5, Serpina5 |