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Product Name | Recombinant human MCM7 protein |
Description | Domain: 1-414aa. Recombinant human MCM7 protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 48.6 kDa (437aa). Purity > 85% by SDS-PAGE. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB |
Size | 20ug, 100ug, 500ug |
Concentration | 0.5mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE,Denatured |
Other Names | DNA replication licensing factor MCM7 isoform 2, CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146 |
Gene, Accession, CAS # | NCBI: NP_877577, UniProt: P33993 |
Catalog # | ATGP2524 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human MCM7 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |