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Product Name | Recombinant human CEBP alpha/CEBPA protein |
Description | Domain: 270-358aa. CCAAT/enhancer binding protein (C/EBP) alpha is a family of transcription factors that all contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in dimerization and DNA binding. C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP family consist of several related proteins, C/EBP alpha, beta, gamma, delta, that form homodimers and that form heterodimers with each other. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein; a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. C/EBPs differ significantly in their physiological functions and in their downstream target genes. For example, mice lacking C/EBP alpha die shortly after birth due to severe hypoglycemia and the absence of glycogen storage in liver, whereas knockout of C/EBPbeta causes defects in female reproduction The bZip region of CEBP-alpha (residues 270-358) was produced in E. coli and purified by ion-exchange chromatography and FPLC gel-filtration chromatography. MW: 14.5 kDa (126aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. |
Size | 20ug, 100ug, 500ug |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | CCAAT/enhancer-binding protein alpha, C/EBP alpha, CEBP |
Gene, Accession, CAS # | NCBI: NP_004355, UniProt: P49715 |
Catalog # | CBP3001 |
Price | $55, $170, $505 |
Order / More Info | Recombinant human CEBP alpha/CEBPA protein from NKMAX Co. Ltd. |
Product Specific References | n/a |