Recombinant human Sepiapterin reductase/SPR protein from NKMAX Co. Ltd.
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| Product Name | Recombinant human Sepiapterin reductase/SPR protein |
| Description | Domain: 1-261aa. Recombinant human SPR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. MW: 30.2 kDa (281aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. Sepiapterin reductase (SPR) belongs to the short-chain dehydrogenase/reductase (SDR) family and also reduces various exogenous carbonyl compounds including phenylpropanedione. SPR is an essential enzyme for the biosynthesis of tetrahydrobiopterin, an essential cofactor for aromatic amino acid hydrolases including tyrosine hydroxylase, the rate-limiting enzyme in dopamine synthesis. Defects in SPR cause DOPA-responsive dystonia defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures |
| Size | 20ug, 100ug, 500ug |
| Concentration | 0.5mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE |
| Other Names | SPR, Sepiapterin reductase, SDR38C1, Short chain dehydrogenase/reductase family 38C, member 1 |
| Gene, Accession, CAS # | NCBI: NP_003115, UniProt: P35270 |
| Catalog # | ATGP0288 |
| Price | $80, $240, $720 |
| Order / More Info | Recombinant human Sepiapterin reductase/SPR protein from NKMAX Co. Ltd. |
| Product Specific References | n/a |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
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