Edit |   |
---|---|
Product Name | Recombinant human S6K1/RPS6KB1 protein |
Description | Domain: 1-525aa. Recombinant human RPS6KB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 60.2 kDa (533aa). Purity > 85% by SDS-PAGE. RPS6KB1, also known as ribosomal protein S6 kinase beta-1 isoform a, is a serine/threonine kinase that acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pathway. Phosphorylation of S6 induces protein synthesis at the ribosome. The phosphorylation of p70S6K at threonine 389 has been used as a hallmark of activation by mTOR and correlated with autophagy inhibition in various situations. However, several recent studies suggest that the activity of p70S6K plays a more positive role in the increase of autophagy |
Size | 10ug, 50ug |
Concentration | 0.25mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | STK14A, Serine/threonine-protein kinase 14A, S6K-beta-1, S6K1, S6K, RPS6KB1, Ribosomal protein S6 kinase I, Ribosomal protein S6 kinase beta-1 isoform a, PS6K, P70S6K1, p70-S6K, p70-alpha, p70(S6K)-alpha, p70 S6KA, p70 S6 kinase alpha, p70 ribosomal S6 kinase alpha, 70 kDa ribosomal protein S6 kinase 1 |
Gene, Accession, CAS # | NCBI: NP_003152, UniProt: P23443 |
Catalog # | ATGP3741 |
Price | $240, $960 |
Order / More Info | Recombinant human S6K1/RPS6KB1 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |