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Product Name | Recombinant human Complement Factor B protein |
Description | Domain: 26-259aa. Recombinant human CFB protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 27.3 kDa (245aa). Purity > 95% by SDS-PAGE. CFB, also known as complement factor B, is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation |
Size | 10ug, 50ug, 250ug |
Concentration | 0.5mg/ml (determined by absorbance at 280nm) |
Applications | SDS-PAGE |
Other Names | Complement factor B, CFB, AHUS4, ARMD14, BF, BFD, CFAB, CFBD, FB, FBI12, GBG, H2-Bf, PBF2 |
Gene, Accession, CAS # | NCBI: NP_001701, UniProt: P00751 |
Catalog # | ATGP3540 |
Price | $80, $240, $960 |
Order / More Info | Recombinant human Complement Factor B protein from NKMAX Co. Ltd. |
Product Specific References | n/a |