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Product Name | Recombinant human MafG protein |
Description | Domain: 1-162aa. Recombinant human MAFG protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. MW: 20 kDa (182aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. MAFG, also known as transcription factor MafG, belongs to the Maf family. Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor |
Size | 10ug, 50ug, 250ug |
Concentration | 0.25mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Transcription factor MafG, hMAF |
Gene, Accession, CAS # | NCBI: NP_116100.2, UniProt: O15525 |
Catalog # | ATGP1268 |
Price | $105, $320, $960 |
Order / More Info | Recombinant human MafG protein from NKMAX Co. Ltd. |
Product Specific References | Lacher SE, et al. Beyond antioxidant genes in the ancient NRF2 regulatory network. (Free Radic Biol Med. 2015){https://pubmed.ncbi.nlm.nih.gov/26163000/};; Lacher SE, et al. A hypermorphic antioxidant response element is associated with increased MS4A6A expression and Alzheimers disease. (Redox Biol. 2018){https://pubmed.ncbi.nlm.nih.gov/29179108/};; Lacher SE, et al. An antioxidant response element regulates the HIF1α axis in breast cancer cells. (Free Radic Biol Med. 2023){https://pubmed.ncbi.nlm.nih.gov/37179033/} |