Edit |   |
---|---|
Product Name | Recombinant human RNA polymerase II subunit RPB11-b1/POLR2J2 protein |
Description | Domain: 1-115aa. Recombinant human POLR2J2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 15.5 kDa (138aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. POLR2J2 is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22. 1 and a pseudogene on chromosome 7p13. The founding member of family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo |
Size | 10ug, 50ug, 250ug |
Concentration | 0.25mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | DNA-directed RNA polymerase II subunit RPB11-b1, HRPB11B, RPB11b1 |
Gene, Accession, CAS # | NCBI: NP_116581, UniProt: Q9GZM3 |
Catalog # | ATGP1952 |
Price | $105, $320, $960 |
Order / More Info | Recombinant human RNA polymerase II subunit RPB11-b1/POLR2J2 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |