Recombinant human c-kit Ligand/SCF protein from NKMAX Co. Ltd.
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| Product Name | Recombinant human c-kit Ligand/SCF protein |
| Description | Domain: 26-189aa. Recombinant human SCF was expressed in E. coli and purified by conventional column chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. MW: 18.5 kDa (165aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. Stem Cell Factor (SCF) is a glycoprotein that plays a key role in hematopoiesis acting both as a positive and negative regulator, often in synergy with other cytokines. SCF binds to and activates the SCF receptor (SCFR), a receptor tyrosine kinase. SCF stimulates the proliferation of mast cells and is able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. It also mediates cell-cell adhesion and acts synergistically with other cytokine |
| Size | 20ug, 100ug, 500ug |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE |
| Other Names | Kit ligand, KITLG, Mast cell growth factor, MGF, Stem cell factor, SCF, c-Kit ligand, steel factor, SF, Kitl, KL-1, Familial progressive hyperpigmentation 2, FPH2, SLF, DFNA69 |
| Gene, Accession, CAS # | NCBI: NP_000890.1, UniProt: P21583 |
| Catalog # | SCF0601 |
| Price | $80, $240, $720 |
| Order / More Info | Recombinant human c-kit Ligand/SCF protein from NKMAX Co. Ltd. |
| Product Specific References | Lee SH, et al. Involvement of MITF-A, an alternative isoform of mi transcription factor, on the expression of tryptase gene in human mast cells. (Exp Mol Med. 2010){https://pubmed.ncbi.nlm.nih.gov/20513998/};;Takahashi M, et al. CD133 is a positive marker for a distinct class of primitive human cord blood-derived CD34-negative hematopoietic stem cells. (Leukemia. 2014){https://pubmed.ncbi.nlm.nih.gov/24189293/}Yamada T, et al. CXCL12 regulates differentiation of human immature melanocyte precursors as well as their migration. (Arch Dermatol Res. 2019){https://pubmed.ncbi.nlm.nih.gov/30483878/} |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
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