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Product Name | Recombinant human c-Jun protein |
Description | Domain: 1-241aa. Recombinant human c-Jun protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 27.3 kDa (261aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. The human protooncogene c-Jun is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. c-Jun and c-Fos form a complex in the nucleus. AP1 is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21, p19 and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons |
Size | 10ug, 50ug |
Concentration | 0.25mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Transcription factor AP-1, AP-1, AP1, c-Jun, jun proto-oncogene |
Gene, Accession, CAS # | NCBI: NP_002219, UniProt: P05412 |
Catalog # | ATGP0960 |
Price | $240, $720 |
Order / More Info | Recombinant human c-Jun protein from NKMAX Co. Ltd. |
Product Specific References | n/a |