Edit |   |
---|---|
Product Name | Recombinant human MAT1A protein |
Description | Domain: 1-395aa. Recombinant human MAT1A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 45.8 kDa (415aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. MAT1A catalyzes the formation of S-adenosyltransferase (AdoMet) for methionine catabolism in the liver. MAT1A expression also correlates with a differentiated phenotype, whereas liver cells expressing MAT2A present a dedifferentiated phenotype and lowered AdoMet synthesis. Likewise, NFkappaB and TNFalpha cause a switch from MAT1A to MAT2A expression in human hepatocellular carcinoma (HCC), which facilitates cancer cell growth |
Size | 10ug, 50ug, 250ug |
Concentration | 0.5mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | S-adenosylmethionine synthetase, MAT, MATA1, SAMS, SAMS1, methionine adenosyltransferase I alpha, S-adenosylmethionine synthetase, MAT1A, |
Gene, Accession, CAS # | NCBI: NP_000420.1, UniProt: Q00266 |
Catalog # | ATGP0489 |
Price | $105, $320, $960 |
Order / More Info | Recombinant human MAT1A protein from NKMAX Co. Ltd. |
Product Specific References | n/a |