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Product Name | Recombinant human CHMP4A protein |
Description | Domain: 1-265aa. Recombinant human CHMP4A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 31.9kDa (285aa) confirmed by MALDI-TOF. Purity > 85% by SDS-PAGE. CHMP4A (Chromatin-modifying protein 4a) belongs to the SNF7 family and functions as chromatin-modifying proteins. It probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. Also during HIV-1 infection, the virus uses the ESCRT-III complex to mediate budding and exocytosis of viral proteins via the association of CHMP4 and a protein recruited by HIV-1 p6, which is present in viral Gag assembly and budding. CHMP4A expressed at higher level in heart, kidney, liver and skeletal muscle |
Size | 10ug, 50ug |
Concentration | 0.25mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Charged multivesicular body protein 4A, Chromatin-modifying protein 4a, CHMP4a, SNF7 homolog associated with Alix-2, SNF7-1, hSnf-1, Vacuolar protein sorting-associated protein 32-1, Vps32-1, hVps32-1, HSPC134, VPS32A |
Gene, Accession, CAS # | NCBI: NP_054888, UniProt: Q9BY43 |
Catalog # | ATGP1376 |
Price | $240, $720 |
Order / More Info | Recombinant human CHMP4A protein from NKMAX Co. Ltd. |
Product Specific References | n/a |