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Product Name | Recombinant human SPG21 protein |
Description | Domain: 1-308aa. Recombinant human SPG21 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. MW: 37.1 kDa (328aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. Spastic paraplegia 21 (SPG21), also known as Maspardin, binds to the hydrophobic C-terminal amino acids of CD4 and may play a role as a negative regulatory factor in CD4-depenent T-cell activation. This protein is widely expressed in various tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Mutations in SPG21 cause Mast syndrome, an autosomal-recessive complicated form of hereditary spastic paraplegia characterized by dementia, thin corpus callosum and white matter abnormalities |
Size | 20ug, 100ug, 500ug |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Spastic paraplegia 21 isoform a, ACP33, BM-019, GL010, Maspardin, MAST, Spastic paraplegia 21 isoform a Acid cluster protein 33, BM019, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, SPG21. |
Gene, Accession, CAS # | NCBI: NP_057714, UniProt: Q9NZD8 |
Catalog # | ATGP0287 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human SPG21 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |