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Product Name | Interleukin-33 (IL-33) |
Description | Purity >95% by SDS-PAGE. Interleukin 33 (IL-33) is a proimflammatory cytokine belonging to the IL-1 family. IL-33 is cleaved in vivo, generating an N terminal and a C terminal fragment. The C terminal fragment corresponds to the mature IL-33 protein and mediates its biological effect by interacting with the IL-1 receptor, also known as ST2. Binding of mature IL-33 to this receptor activates NF-kappa B and MAP kinases and induces the production of associated cytokines in particular IL-4, IL-5 and IL-13 causing severe pathological changes in mucosal organs. |
Size | 100µg |
Concentration | n/a |
Applications | RUO |
Other Names | Recombinant protein. Interleukin 33; Nuclear factor from high endothelial venules; NFHEV, Chromosone 9 open reading frame 26; C9ORF26; Interleukin-1 family member 11; IL-1F11. |
Gene, Accession, CAS # | n/a |
Catalog # | RCP9416 |
Price | $435 |
Order / More Info | Interleukin-33 (IL-33) from RANDOX LABORATORIES LTD. |
Product Specific References | Schmitz J. et al. (2005), Immunity. 23(5): 479-90. |