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Product Name | Pro-Matrix Metalloproteinase 9 (PRO MMP-9) |
Description | Purity >95% by SDS-PAGE. Matrix metalloproteinases are a family of zinc- and calcium-dependant endopeptidases, which degrade extracellular matrix proteins. MMP-9 is secreted as a 92kDa zymogen. Cleavage of pro-MMP-9 results in the active enzyme with a molecular weight of ~82kDa. MMP-9 has a gelatin-binding domain consisting of three fibronectin type II units, a catalytic domain containing the zinc-binding site, a proline-rich type V collagen homologous domain and a hemopexin-like domain. MMP9 is produced by monocytes, macrophages, neutrophils, keratinocytes, fibroblasts, osteoclasts and endothelial cells, and is involved in inflammatory responses, tissue remodelling, wound healing, tumour growth and metastasis. |
Size | 100µg |
Concentration | n/a |
Applications | RUO |
Other Names | Recombinant protein. Matrix metalloproteinase 9, gelatinase B, 92kD gelatinase, 92kD type IV collagenase precursor, CLG4B, GELB |
Gene, Accession, CAS # | n/a |
Catalog # | RCP9380 |
Price | $468 |
Order / More Info | Pro-Matrix Metalloproteinase 9 (PRO MMP-9) from RANDOX LABORATORIES LTD. |
Product Specific References | Pourmotabbed, T et al., Biochim Biophys Acta. 1204 (1):97-107(1994). Romanic, AM. et al., Stroke 29 (5): 1020-1030 (1998). |