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Product Name | Integrin-Linked Kinase (ILK) |
Description | Purity >95% by SDS-PAGE. Integrin-linked kinase (ILK1) is a serine/threonine protein kinase, containing 4 ankyrin-like repeats. ILK1 interacts with the cytoplasmic domains of integrin β1 and β3 subunits as well as several adaptors and signalling proteins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. ILK1 has been reported to regulate a number of biological properties including anchorage independent cell cycle progression, tumour cell invasion and apoptosis. Over-expression of ILK1 has been documented in a wide variety of human malignancies. RANDOX recombinant ILK1 comprises a 452 amino acid fragment (1-452) corresponding to the mature ILK1 full-length protein and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use. |
Size | 100µg |
Concentration | n/a |
Applications | RUO |
Other Names | Recombinant protein. ILK-1, ILK-2, 59 kDa serine/threonine-protein kinase, p59, p59ILK. |
Gene, Accession, CAS # | n/a |
Catalog # | RCP9199 |
Price | $457 |
Order / More Info | Integrin-Linked Kinase (ILK) from RANDOX LABORATORIES LTD. |
Product Specific References | Hannigan G.E. et al Nature. 1996. 379 (6560) : 91-6. Marotta A. et al, BJC 2003 88 :1755-1762 |