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Product Name | Human ALCAM ELISA Kit |
Description | Specificity: Natural and recombinant human ALCAM. There is no detectable cross-reactivity with other relevant proteins. CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins. In humans it is encoded by the ALCAM gene. The gene was mapped to human chromosome 3q13.1-q13.2 by fluorescence in situ hybridization of cDNA probes to metaphase chromosomes. It is also called CD166(cluster of differentiation 166), MEMD, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. It is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, neurons, melanoma cells, and also in sweat and sebaceous glands. CD166 protein expression is reported to be upregulated in a cell line deriving from a metastasizing melanoma. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development. Recently, CD166 has also been used as a potential cancer stem cell marker. |
Size | 1 kit |
Concentration | n/a |
Applications | ELISA |
Other Names | Activated leukocyte cell adhesion molecule, ALCAM, ALCAM protein, CD 166, CD166, CD166 antigen, CD166_HUMAN, FLJ3851, FLJ38514, MEMD, MGC71733 |
Gene, Accession, CAS # | ALCAM, Gene ID: 214, NCBI: NP_001230209.1, UniProt: Q13740 |
Catalog # | KOA0621 |
Price | $589 |
Order / More Info | Human ALCAM ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |