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Product Name | Human Angiopoietin-2 ELISA Kit |
Description | Specificity: Natural and recombinant human Angiopoietin-2. There is no detectable cross-reactivity with other relevant proteins. Angiopoietin 1 and Angiopoietin 2 are important for development of the endothelium, by regulating tyrosine phosphorylation of the membrane receptor Tie 2. Angiopoietin 2 is only 60% homologous with Angiopoietin 1. Angiopoietin-2 is a naturally occurring antagonist of angiopoietin-1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation. Angiopoietin 1 binding to Tie 2 causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding, and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches, ovary, placenta and uterus. |
Size | 1 kit |
Concentration | n/a |
Applications | ELISA |
Other Names | AGPT2, ANG 2, ANG-2, ANG2, Angiopoietin 2a, Angiopoietin 2B, Angiopoietin-2, Angiopoietin2, ANGP2_HUMAN, ANGPT 2, Angpt2, Tie2 ligand |
Gene, Accession, CAS # | ANGPT2, Gene ID: 285, NCBI: NP_001112359.1, UniProt: O15123 |
Catalog # | KOA0374 |
Price | $589 |
Order / More Info | Human Angiopoietin-2 ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |