Description | Specificity: Natural and recombinant human ADAM8. There is no detectable cross-reactivity with other relevant proteins. A Disintegrin and metalloproteinase domain-containing protein 8 is an enzyme that in humans is encoded by the ADAM8 gene. ADAM8 is localized to chromosome 10q26.3. This gene encodes a member of the ADAM (a disintegrin and metalloproteinase domain) family. Members of the ADAM family, such as ADAM8, are cell surface proteases involved in remodeling of extracellular matrix, cell migration, and processing of membrane-bound signaling molecules. They are characterized by disintegrin and metalloprotease domains that confer adhesive properties and proteolytic activities, respectively. And the protein encoded by this gene may be involved in cell adhesion during neurodegeneration. |
Other Names | A Disintegrin And Metalloproteinase domain 8, ADAM 8, ADAM 8 precursor, ADAM metallopeptidase domain 8, Adam8, ADAM8_HUMAN, CD 156, CD156, CD156a, CD156a antigen, CD156a antigen, Cell surface antigen MS2, Cell surface antigen MS2, Disintegrin and metalloproteinase domain-containing protein 8, Human leukocyte differentiation antigen, Human leukocyte differentiation antigen, Macrophage cysteine rich glycoprotein, MGC134985, MS 2, MS2 |